
Cannabis
{Weed, marijuana, kush, pot, hash, skunk}
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Dose and onset
How? How Much? When? For how Long?
Read our sections on dosing and tolerance for more information.
The effects you experience from a given dose of cannabis depends on many different details about the user, such as their weight, the speed of their metabolism, their past experiences and the situation in which the cannabis is consumed.
The same is true of every other drug, but with cannabis, it is especially difficult to identify one’s ideal quantity, due to the variety of strains, the way you consume it, and the distribution of the active compounds in the buds.
How you take it matters...
From the healthiest to the most harmful way:
Spray
This route of administration is the healthiest, but it can only be obtained with a medical prescription in countries where this is legal and sold. As such, it is barely used among recreational drug users, who for the most part are left with more calorific or carcinogenic alternatives. Sativex is the most widely-known spray. It contains high levels of both THC and CBD, and takes around 15 minutes to kick in.
Vaping/Vaporisation
Vaping involves heating up cannabis to release THC and other cannabinoids. Vaping is, crucially, a cleaner alternative to combustion (i.e. smoking/inhaling). The heating process creates a temperature cool enough to avoid creating the toxins that appear during combustion. Therefore, vaping is likely to reduce the coughing and throat irritation associated with smoking. It also doesn’t require any tobacco, and therefore may reduce tobacco addiction in cannabis users (3,7,8). This may be the most expensive method of administration, because of the price of the vaporiser. However, vaporising could be a cost-effective method in the long term8,9.
Read about how vaporisation works.
Eating
Eating is probably the easiest and safest way to consume cannabis. However, eating cannabis is not without dangers: users anticipate similar timing and effects to when they are vaping/smoking/inhaling, but the effects take much longer (up to 2 hours) when consuming edibles. Therefore, it’s tempting to re-dose before the high comes on. Be patient: if the first dose wasn't strong enough, try a higher dose another day. Re-dosing is the easiest way to overdose! People normally feel that edibles give them a “body high,” this is because the compounds in cannabis are slightly altered by the stomach, intestine and liver.
Inhaling
Cannabis can be inhaled through a pipe or a bong. While it's less harmful than smoking, it is easier to inhale greater quantities of smoke. Users should be careful not to breathe too deeply in order to regulate their high. Bongs with ice catchers can reduce the irritation of the throat as the ice cools down the smoke.
Smoking
Smoking cannabis is the most common way to consuming cannabis, even though it’s the unhealthiest. This method increases the probability of developing lung cancer because burning cannabis (with or without tobacco) creates toxins associated with cancer. In Europe, cannabis is often mixed with a much deadlier companion: tobacco. Adding tobacco to your cannabis increases the chances of throat irritation, and also increases the risks of cancer and dependence. We recommend to avoid smoking cannabis, but if you do instead of using tobacco you could use herbal smoking blends without nicotine and other toxins found in tobacco.
How much?
Smoking
Every time you try a new strain, or use a different supplier, smoke a smaller dose than you are used to, so you can notice variations in the effects and potency of the drug (we define potency as the amount of active ingredient required to produce a desired effect).
- Light dose: 0.05 g
- Common dose: 0.15 g
- Strong dose: 0.25 g
For someone consuming the average dose, a one gram bag of cannabis will last between 8–12 smokes, if you roll your joints with king skins and mix your weed with tobacco.
Eating
When you cook edibles, there are even more factors that influence the effects you'll get from the food. Some of these are: the strain you are using, whether you are using oil or butter, the time you leave it cooking, the strength of the heat (low heat, between 1-2 hours in a saucepan is optimum), and of course, your culinary skills...
- Light dose: 2.5 - 5 mg (THC)
- Medium dose: 5-25 mg (THC)
- Strong dose: 25 mg (THC)
When do the effects kick in?
The START time below is when you will usually begin to feel the effects of cannabis from the time when you first take it. DURATION is roughly the length of time you will experience the effects, after which the effects will start to wind down and you might start to feel the comedown effects.
Smoking
- START: 2-10 minutes
- DURATION: 2-8 hours
Eating
- START: 20-120 minutes (depends on stomach content)
- DURATION: 3-9 hours
Kief is the resin that falls off dry cannabis or what accumulates in grinders. It is the strongest part and contains high concentrations of THC. Watch out for this.
How often can I take it?
Consuming cannabis too often decreases the potency of this drug on your body. This may lead to consuming larger amounts of cannabis. Save cannabis for special occasions or events only, and use it sparingly.
References
1 Crean, R. D., Crane, N. A., & Mason, B. J. (2011). An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions. Journal of addiction medicine, 5(1), 1.
2 Curran, H. V., Freeman, T. P., Mokrysz, C., Lewis, D. A., Morgan, C. J., & Parsons, L. H. (2016).Keep off the grass? Cannabis, cognition and addiction. Nature Reviews Neuroscience, 17(5), 293-306.
3 Earleywine M, Barnwell SS. Decreased respiratory symptoms in cannabis users who vaporize. Harm Reduct J (2007) 4:11. doi:10.1186/1477-7517-4-11.
4 Filbey, F. M., McQueeny, T., Kadamangudi, S., Bice, C., & Ketcherside, A. (2015). Combined effects of marijuana and nicotine on memory performance and hippocampal volume. Behavioural brain research, 293, 46-53.
5 Freeman, TP., Morgan, C.J.A., Hindocha, C., Schafer, G., & Curran, H.V (2014). Just say 'know': how do cannabinoid concentrations influence users' estimates of cannabis potency and the amount they roll in joints? Addiction 109(10):1686-94; doi: 10.1111/add.12634
6 Hall W, Room R, Bondy S. Comparing the health and psychological risks of alcohol, cannabis, nicotine and opiate use. In: Kalant H, Corrigan W, Hall W, Smart R, eds. The health effects of cannabis. Toronto: Addiction Research Foundation, 1999, pp. 477-508.
7 Hindocha, C Freeman, T.P., WInstock, A.R, Lynskey, M.T. (2016) Vaping cannabis (marijuana) has the potential to reduce tobacco smoking in cannabis users. Addiction 111(2); 375 -- 375; doi: 10.1111/add.13190.
8 Hindocha, C., Freeman, T.P., Ferris, J.A., Lynskey, M.T., & Winstock, A.R., (2016) No Smoke without tobacco? A global overview of cannabis and tobacco routes of administration and their association with intention to quit. Front Psychiatry, 7, 104.
9 Hindocha, C., Shaban, N. D., Freeman, T. P., Das, R. K., Gale, G., Schafer, G., ... & Curran, H. V. (2015). Associations between cigarette smoking and cannabis dependence: a longitudinal study of young cannabis users in the United Kingdom. Drug & Alcohol Dependence, 148, 165-171.
10 <https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/664945/Young-people-statistics-report-from-the-national-drug-treatment-monitoring-system-2016-2017.pdf>
11 <https://www.erowid.org/plants/cannabis/cannabis_dose.shtml>
12 <https://www.globaldrugsurvey.com/wp-content/uploads/2014/04/Printable_Cannabis1.pdf>
13 <http://www.drugscience.org/dl/dl_comparison.html>
14 Iversen, L. L. (2001). The science of marijuana. Oxford University Press.
15 Kleiber D, Soellner R, Tossmann P. Cannabiskonsum in der Bundesrepublik Deutschland: Entwicklungstendenzen, Konsummuster und Einflußfaktoren. Bonn: Bundesministerium für Gesundheit, 1997.
16 Kouri EM, Pope HG. Abstinence symptoms during withdrawal from chronic marijuana use. Exp Clin Psychopharmacol 2000;8(4):483-92.
17 Nutt, D. (2012). Drugs without the hot air. Minimising the Harms of Legal and Illegal Drugs. Cambridge: UIT Cambridge Ltd Nutt, D. J., King, L. A., & Phillips, L. D. (2010).
18 Piomelli, D., & Russo, E. B. (2016). The cannabis sativa versus cannabis indica debate: an interview with Ethan Russo, MD. Cannabis and Cannabinoid Research, 1(1), 44-46.
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