2C-B
{Nexus, Bees, Venus, Bromo mescaline}
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Dose and onset
How? How Much? When? For how Long?
As with any drug, the correct dose for you depends on factors such as weight, gender, metabolism, whether you have taken the drug recently or not, amongst many others.
Read our section on dosing and tolerance for more information.
How you take 2C-B matters
The least harmful way to consume 2C-B is orally: either via ingestion, which can mean swallowing a pill, “bombing” (wrapping 2C-B powder in cigarette paper and swallowing it) 10 or “gumming”, where the drug is rubbed into the gums with a fingertip.
Nasal intake has been reported to be extremely painful and is best avoided 11. Due to this we recommend avoiding this method of consumption. It is worth noting that taking the powder through the nose results in a much faster onset and a shorter total duration 12. There are reports of people smoking 2C-B, however the responses vary widely: some experiencing negative effects, minimal effects or none at all. It also makes it easier to take too much.
How much 2C-B?
- Threshold - 2-5 mg
- Light - 5-15 mg
- Common - 15-25 mg
- Strong - 25-50 mg (taking any amount greater than 50 mg puts the user at serious risk of adverse effects) 13.
Source: erowid.org
When do the effects of 2C-B kick in and for how long?
The main effects will likely last between 4 and 8 hours depending on the dose, the individual and the contents of their stomach. If taken orally without being on an empty stomach the onset can be delayed while the effects are slightly prolonged but also slightly diminished.
Oral 14:
- Onset: 45-75 minutes
- Come-up: 15-30 minutes
- Plateau: 2-4 hours
- Come-down: 1-2 hours
- After effects: 2-4 hours
Nasal:
- Onset: 1-10 minutes
- Duration: 2-4 hours
- Come-down: 1-2 hours
- After-effects: 2-4 hours
Source: erowid.org
How often can I take 2C-B?
If you know of any good source containing this information please email us to contact@drugsand.me. We'll credit you in our Team section! Thanks :)
References
1 "2C-B Street Names" (PDF). February 1, 2011.
2 "2C-B (Nexus) Reappears on the Club Drug Scene" (PDF). National Drug Intelligence Center. Department of Justice. May 2001.
3 Pharmacological Studies of Some Psychoactive Phenylalkylamines-Entactogens, Hallucinogens, and Anorectics, Nicholas Cozzi.
4 Caudevilla-Galligo, F.; Riba, J.; Ventura, M.; González, D.; Farré, M.; Barbanoj, M. J.; Bouso, J. C. (2012). "4-Bromo-2,5-dimethoxyphenethylamine (2C-B): Presence in the recreational drug market in Spain, pattern of use and subjective effects". Journal of Psychopharmacology.
5 "Erowid 2C-B Vault: Basics". Erowid
6 https://en.wikipedia.org/wiki/Synesthesia
7 Gonzalez D, Torrens M, Acute Effects of the Novel Psychoactive Drug 2C-B on Emotions.
8 Carmo, H.; Hengstler, J. G.; De Boer, D. D.; et al. (2005). "Metabolic pathways of 4-bromo-2,5-dimethoxyphenethylamine (2C-B): Analysis of phase I metabolism with hepatocytes of six species including human". Toxicology. 206 (1): 75--89. doi:10.1016/j.tox.2004.07.004. PMID 15590110
9 <http://drugs.tripsit.me/2c-b>
10 http://www.synchronium.net/2010/05/06/how-to-make-a-bomb/
11 https://erowid.org/chemicals/2cb/2cb_faq.shtml
12 "Erowid 2C-B Vault: Effects". Erowid. Retrieved 2018-01-02.
13 De Boer, D.; Gijzels, M. J.; Bosman, I. J.; Maes, R. A. A. (1999). "More Data About the New Psychoactive Drug 2C-B". Journal of Analytical Toxicology.
14 "Erowid 2C-B Vault: Basics". Erowid. 2011-02-20
15 Kanamori, Tatsuyuki, et al. In vivo metabolism of 4-bromo-2, 5-dimethoxyphenethylamine (2C-B) in the rat: identification of urinary metabolites. Journal of analytical toxicology 26.2 (2002): 61-66.
16 https://www.webmd.com/depression/guide/serotonin-syndrome-causes-symptoms-treatments#1
17 Boyer, Edward W.; Shannon, Michael (2005). "The Serotonin Syndrome". New England Journal of Medicine. 352 (11): 1112--20
18 https://www.reddit.com/r/Drugs/comments/2sxvbd/bestbenzoforacome_down/
19 GOV.UK, Controlled Substances, Retrieved from <https://www.gov.uk/government/publications/controlled-drugs-list--2/list-of-most-commonly-encountered-drugs-currently-controlled-under-the-misuse-of-drugs-legislation>, 01/02/2018
20 Misuse of Drugs Act 1971. Retrieved from <https://www.legislation.gov.uk/ukpga/1971/38/contents>
21 "List of psychotropic substances under international control"(PDF).
22 UK Government, most commonly encountered illegal drugs, <https://www.gov.uk/government/publications/controlled-drugs-list--2/list-of-most-commonly-encountered-drugs-currently-controlled-under-the-misuse-of-drugs-legislation>
23 "Clinical Pharmacology of SSRI's: Why Are CYP Enzymes Important When Considering SSRIs?
24 Tatsumi M, Groshan K, Blakely RD, Richelson E (1997). "Pharmacological profile of antidepressants and related compounds at human monoamine transporters". Eur J Pharmacol.
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