MDMA is a stimulant-hallucinogenic research chemical. MDMA is not the same drug as ecstasy. Ecstasy is usually combined with other substances, from caffeine to amphetamine!

Please read ME for more general information about recreational drugs.


Don't redose too soon


Drink water


Take breaks


We have listed the most common effects of MDMA. Please note that everyone can be affected differently, and this is not an exhaustive list. Not everyone experiences these effects, and other effects are possible. Remember that negative side effects of MDMA increase with higher doses.

The effects are (from positive to negative):

    • Mood lift (mild to extreme)
    • Talkative and sociable
    • Increase in energy
    • Feelings of comfort and belonging
    • Increased empathy
    • Increased appreciation of music
    • Increased pleasure from the sense of touch
    • Decreased appetite
    • Visual distortion: mild hallucinations
    • Rapid involuntary eye jiggling
    • Change in body temperature regulation
    • Unexpected emotions
    • Strong desire to take more MDMA when coming down
    • Mild to extreme jaw clenching, tongue and cheek chewing, and teeth grinding
    • Difficulty concentrating
    • Impaired ability to focus eyes/blurred vision
    • Inability to fall asleep when physically tired
    • Erectile dysfunction and difficulty reaching orgasm
    • Increase in body temperature, dehydration
    • Nausea and vomiting

    source: and

* Much more common among first-time users

Dose and Onset

How? How much? When? For how long?

Please read ME for more general information about recreational drugs.

As with any drug, the correct dose for you depends on factors such as weight, gender, metabolism, whether you have taken the drug recently or not, amongst many others.

How you take it matters...

MDMA usually comes in a powder or pill form, and is ingested orally. However, it is also sometimes taken nasally, but this is not recommended, as it decreases the length of the experience, cause nasal pain and can cause a more severe comedown.

How much?

  • Small/sensitive people/first timers: 60-90mg
  • Recommended dose for most people: 75-125mg
  • Large/less sensitive people: 110-150mg
  • Strong dose: 150-200mg
  • Heavy dose: 200mg+

Guideline by body weight: 0.7mg per lb, or 1.54mg per kg

Optional redose: half of the original dose, 2–3 hours in.

Use a scale to measure the exact amount of MDMA you would like to take.

Sources: and

When do the effects kick in and for how long?

The START time below is when you will usually begin to feel the effects of MDMA from the time when you first take it. DURATION is roughly the length of time you will experience the effects, after which the effects will start to wear off and you might start to feel the comedown effects.

  • Onset: 20–70 minutes (depending on the form of the MDMA and how much food you have eaten)
  • Duration: 3–5 hours
  • Normal after-effects: up to 24 hours after


WARNING: pills in the UK and Europe contain a very high concentration of MDMA. This can lead to accidental overdoses. We recommend that you try half a pill first as it might have much more MDMA than you expect.

How often can I take it?

The Three Month Rule

MDMA works by causing large amounts of serotonin to be released, along with other neurotransmitters like dopamine. After using MDMA, your serotonin levels are lowered, and it takes a long time for your brain to build more serotonin. If you take ecstasy on a regular basis, you may be releasing and depleting your serotonin before it has a chance to fully replenish itself. This means you will be operating on lower-than-normal serotonin levels most of the time, and this can lead to depression or worsen depressive symptoms. It is recommended that you leave at the very least 1–2 months between uses, ideally 3. Save MDMA for special occasions or events only, and use it very sparingly.

Tolerance and loss of effectiveness

Consuming MDMA too often decreases the potency of this drug on your body. This may lead to consuming larger amounts of MDMA. Again, save MDMA for special occasions or events only, and use it very sparingly.


+ ? =

dangerous to synergy bar


Click one of the drugs below and see how it mixes with .



Harm reduction

Please read ME for more general information about recreational drugs.

There are certain precautions you should take before using MDMA. The advice below helps to prepare you both physically and mentally. We want you to be safe and enjoy your experience as much as possible, so if you have a bad experience or are struggling with especially bad after-effects, please take note of the advice below.




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Long-term use and health risks

There are studies that indicate brain toxicity can occur after MDMA use. However, there is little or no knowledge of what the consequences are.

Most of the MDMA-related injuries are due to dehydration caused by increased sweating and overheating. Make sure to drink water during the night, but not too much as too much water can lead to health risks of its own.


MDMA is not as addictive as other stimulants or depressants. However, like any other drug, it is possible to become dependant if it becomes a habit. Please read our information on dependence in our ME page for more information.

The Law


  • UK: Illegal. Class A drug. Penalties include a maximum of seven years and/or unlimited fine for possession; life and/ or unlimited fine for production or trafficking.
  • Germany: Illegal
  • France: Illegal
  • Netherlands: Illegal
  • Spain: Illegal
  • Russia: Illegal
  • Czech Republic: Posession of less than 5 pills is not a serious criminal offense
  • Portugal: Decriminalised up to 1g.
  • Rest of Europe: Illegal in all countries


  • USA: Illegal, Schedule I section D 1995.
  • Canada: Schedule III
  • Mexico: Illegal


  • Australia: Illegal
  • New Zealand: Illegal
  • Singapore: Illegal
  • Hong King: Illegal
  • Israel: Illegal


  • South Africa: Illegal


To learn why MDMA is illegal, watch this video:

More information, references, useful links...


I have a heart problem. Can I take MDMA?

It depends on your condition, however, stimulants can increase your heart rate considerably, so if you want to be on the safe side, it is better to not take it.


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